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Research PubMed / J Int Soc Sports Nutr clinical-researchexercise-physiologygeriatric-pt

Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial.

PubMed / J Int Soc Sports Nutr · 2026-03-21 · By Jeong D, Valentine RJ, Jeong H, et al. · Journal of the International Society of Sports Nutrition

A randomized controlled trial found that combining resistance exercise with essential amino acid supplementation significantly improved the follistatin-to-myostatin ratio in older women, a marker associated with favorable muscle-building conditions. The intervention group demonstrated greater gains in muscle fitness compared to exercise or supplementation alone. These findings suggest a synergistic effect between nutritional support and resistance training that may benefit sarcopenia prevention in aging populations.

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