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The RESOLVE Trial: A Stepped-Wedge, Cluster-Randomized Clinical Trial Evaluating the Effects of Clinical Practice Guidelines and Psychologically Informed Physical Therapy on Low Back Pain Outcomes in Service Members and Veterans.

PubMed / Phys Ther · 2026-07-19 · By Beisheim-Ryan EH, Hendershot BD, Patterson CG, et al. · Physical therapy

The RESOLVE Trial examined whether implementing clinical practice guidelines alongside psychologically informed physical therapy improved low back pain outcomes in military service members and veterans, using a stepped-wedge, cluster-randomized design. This study addresses a high-priority population where musculoskeletal conditions like low back pain carry significant burden. Results from this trial may inform how military and VA physical therapy programs integrate psychological factors into evidence-based LBP management.

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