Clinical and cost-effectiveness of the iStep-MS physical activity and sedentary behaviour intervention for managing fatigue in people with multiple sclerosis: protocol for a multicentre randomised controlled trial.

Researchers have published the protocol for a multicentre randomised controlled trial evaluating the iStep-MS intervention, which targets physical activity and sedentary behaviour to address fatigue in people with multiple sclerosis. The trial will assess both clinical effectiveness and cost-effectiveness of the program. This study is directly relevant to physical therapists who manage MS-related fatigue and develop activity-based rehabilitation strategies.

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