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Research PubMed / Expert Rev Neurother clinical-researchpediatric-ptneuromodulation

HAND-IN (hand function after neuromodulation and intensive training in children with cerebral palsy): study protocol for a randomized, triple-blind, controlled trial with embedded implementation and cost-effectiveness analyses.

PubMed / Expert Rev Neurother · 2026-09-03 · By Vancetto Maglione A, Firmo Dos Santos J, Rodrigues da Silva AC, et al. · Expert review of neurotherapeutics

The HAND-IN trial is a randomized, triple-blind, controlled study examining whether combining transcranial direct current stimulation (tDCS) with intensive hand training improves upper limb function in children with cerebral palsy. The protocol also incorporates implementation and cost-effectiveness analyses alongside the primary clinical outcomes. This research is directly relevant to pediatric physical and occupational therapists working on neuromodulation-assisted rehabilitation for this population.

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