A multimodal manual therapy, exercise, and psychological intervention for painful diabetic neuropathy: the NeuOst feasibility randomised controlled trial.

A feasibility randomized controlled trial called NeuOst examined a combined approach—manual therapy, exercise, and psychological intervention—for managing painful diabetic neuropathy. The study assessed whether this multimodal treatment model could be practically delivered and tested in preparation for a larger trial. Findings from this feasibility phase will help inform the design and methodology of future full-scale RCTs targeting this difficult-to-treat chronic pain condition.

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