Exercise to enhance antipsychotic effectiveness and mitigate metabolic harm: systematic review and meta-analysis.

A systematic review and meta-analysis published in the Journal of Affective Disorders examined whether exercise interventions can boost the clinical effectiveness of antipsychotic medications while reducing their metabolic side effects. The findings suggest that physical activity may serve as a valuable adjunct to antipsychotic treatment, potentially improving psychiatric outcomes and countering metabolic risks such as weight gain and dyslipidemia associated with these drugs. Physical therapists involved in mental health or wellness settings may find these results relevant when designing exercise programs for patients on antipsychotic regimens.

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