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Changes in Gait Speed During a 12-Month Multidisciplinary Obesity Management Program Including Semaglutide: A Real-World Observational Study in Japanese Adults With Musculoskeletal Disorders.

PubMed / Intern Med · 2026-10-15 · By Tomita M, Harashima F, Takeda N, et al. · Internal medicine (Tokyo, Japan)

A real-world observational study examined how gait speed changed over 12 months in Japanese adults with musculoskeletal disorders who participated in a multidisciplinary obesity management program incorporating semaglutide. The findings offer insight into how GLP-1 receptor agonist-based weight management may influence a functional mobility measure highly relevant to physical therapy practice. Gait speed is a recognized clinical outcome for assessing physical function, making this study pertinent to PTs managing patients with obesity-related musculoskeletal conditions.

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